Sleep is the body’s way of metabolically and psychologically resetting itself. The body’s circadian rhythm is regulated by an internal biological clock with an approximate 24-hour cycle. In order to maintain restorative sleep, it is crucial that the brain has optimal levels of serotonin and gamma-aminobutyric acid (GABA), the relaxing and sleep-regulating neurotransmitters, as well as the sleep-regulating hormone melatonin.
The synergistic ingredients in Fundamental Sleep Support, including 5-HTP, PharmaGABA®, and taurine, boost levels of the neurotransmitters and hormones that promote relaxation prior to bedtime and increase the deep, restorative stages of sleep.
5-HTP: The sleep-regulating hormone melatonin requires the essential amino acid, L-tryptophan for conversion. A deficiency of L-tryptophan in the diet can lead to low serotonin and melatonin levels, which can contribute to sleep challenges. L-tryptophan is converted into the amino acid intermediate 5-hydroxytryptophan (5-HTP), which is then converted directly into serotonin, followed by melatonin conversion.
PharmaGABA®: Gamma-amino butyric acid (GABA) is one of the major inhibitory neurotransmitters in the brain. GABA provides a calming effect and plays a direct role in activating the sleep cycle in the evening. Most commercially available forms of GABA utilize synthetically-produced GABA, manufactured from pyrrolidinone, a compound not allowed for use in Japan. Cerenity PM includes a patented, naturally-sourced, non-synthetic form of GABA called PharmaGABA®. In a study utilizing 100 mg of PharmaGABA®, supplemented before bedtime, PharmaGABA® was shown to reduce sleep latency by 20%, while increasing time spent in a deep sleep by 20%.
PHOSPHATIDYLSERINE (PS) is a phospholipid found in high concentrations in the brain. Phosphatidylserine has been shown to play a role in regulating cortisol excretion. Elevated levels of cortisol throughout the night can contribute to frequent waking. When taken in the evening, PS can help reduce cortisol excretion from the body’s stress response system, the hypothalamic-pituitaryadrenal (HPA) axis, in order to promote a healthy sleep cycle.
TAURINE is an amino acid that is found abundantly in the brain and has neuroprotective properties. Taurine promotes inhibitory neurotransmission by activating GABA receptors. Taurine also supports inhibitory neurotransmission by activating glycine receptors in the brain.
MINERAL BLEND: Calcium and magnesium are two minerals that play a major role in supporting a healthy sleep cycle. Magnesium (Mg) calms the nervous system and has been shown to play a role in the regulation of the HPA axis. Magnesium promotes relaxation by decreasing the activity of glutamate, the primary excitatory (stimulating) neurotransmitter in the brain. Calcium ions are a critical requirement in the synthesis of melatonin. The combination of 5-HTP and calcium in Cerenity PM provides a significant and natural boost to melatonin levels, aiding in the conversion and activation of this crucial sleep hormone.
*This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.===tab===Serving size: 4 capsules
Servings per container: 15 & 30
4 capsules contain:
Vitamin C: 50 mg
(as Ascorbic Acid USP)
Niacin: 10 mg
(as Niacinamide USP)
Vitamin B6: 10 mg
Folate: 680 mcg DFE
(from 400 mcg as Quatrefolic (6s)-5-Methyltetrahydrofolic acid glucosamine salt)
Calcium: 250 mg
(as DimaCal Dicalcium Malate)
Magnesium: 150 mg
(as DiMagnesium Malate)
Zinc: 5 mg
(as TRAACS Zinc Bisglycinate Chelate)
Taurine USP: 300 mg
5-HTP: 150 mg
(5-Hydroxytryptophan) (from Griffonia simplicifolia (Seed))
Gamma Aminobutyric Acid: 150 mg
Phosphatidylserine: 100 mg
(from Sunflower Seed)
Other Ingredients: Natural Vegetable Capsules, Microcrystalline Cellulose, Magnesium Stearate, and Silicon Dioxide.
*This product is formulated to be free of allergens derived from: gluten, artificial colors and flavors.===tab===Directions: Take 4 capsules taken one to two hours before bedtime or as recommended by your health care professional.
Caution: Keep out of the reach of children.
Tamper Evident: Do not use if safety seal is missing or broken.
Storage: Keep tightly closed in a cool, dry place.
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